Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3617
Trial ID NCT06080191
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19-CAR_Lenti_ALLO
Generation2th
PhasePhase1
Recruitment statusRecruiting
TitlePhase I Clinical Trial on the Use of Fresh, Allogeneic, Second-generation CD19-CAR T Cells for Treatment of Children With Relapsed/Refractory B-cell Acute Lymphoblastic Leukemia
Year2024
CountryItaly
Company sponsorBambino Gesù Hospital and Research Institute
Other ID(s)AlloCAR

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E6 cells/kg, 1.0E6 cells/kg, 2.0E6 cells/kg, 3.0E6 cells/kg, 5.0E6 cells/kg
Pts 24
Age Child, Adult
Lymph depletion Yes

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