Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3615
Trial ID NCT06078306
Disease B Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GDC-0199
Co-treatment Azacitidine|Venetoclax
PhasePhase2
Recruitment statusRecruiting
TitleClinical Trial for the Safety and Efficacy of Induction Chemotherapy With Azacitidine+Venetoclax (VA) and Bridging CD19CD22 CAR-T Therapy in Adult Patients With Newly Diagnosed High-Risk and Ph-negative (Ph-) B-ALL
Year2024
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)High Risk B-ALL

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 20
Age Adult, Older_Adult

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