Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3615 |
Trial ID | NCT06078306 |
Disease | B Acute Lymphoblastic Leukemia | Acute Lymphoblastic Leukemia |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | GDC-0199 |
Co-treatment | Azacitidine|Venetoclax |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | Clinical Trial for the Safety and Efficacy of Induction Chemotherapy With Azacitidine+Venetoclax (VA) and Bridging CD19CD22 CAR-T Therapy in Adult Patients With Newly Diagnosed High-Risk and Ph-negative (Ph-) B-ALL |
Year | 2024 |
Country | China |
Company sponsor | The First Affiliated Hospital of Soochow University |
Other ID(s) | High Risk B-ALL |
Cohort 1 | |||||||
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