Basic Information

Gene symbol CTLA4 Synonyms ALPS5, CD, CD152, CELIAC3, CTLA-4, GRD4, GSE, IDDM12 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description cytotoxic T-lymphocyte associated protein 4

GTO ID GTC3613
Trial ID NCT06072989
Disease Solid Tumor
Altered gene CTLA4
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment B4T2-001 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleA Single Arm, Open Label Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Antitumor Activity of B4T2-001 CAR-T in Patients With Advanced Solid Tumors
Year2023
CountryChina
Company sponsorShanghai East Hospital
Other ID(s)B4T2-PRC IIT-001

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 24
Age Adult, Older_Adult

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