Basic Information

Gene symbol CDH17 Synonyms CDH16, HPT-1, HPT1 Type of gene protein-coding
Description cadherin 17

GTO ID GTC3598
Trial ID NCT06055439
Disease Neuroendocrine Tumor | Colorectal Cancer | Gastric Cancer
Altered gene CDH17
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CHM-2101
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Phase 1/2 Study to Evaluate CHM-2101, an Autologous Cadherin 17 (CDH17) Chimeric Antigen Receptor (CAR) T Cell Therapy for the Treatment of Relapsed or Refractory Gastrointestinal Cancers
Year2024
CountryUnited States
Company sponsorChimeric Therapeutics
Other ID(s)CHM-2101-001

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type autologous
Pts 135
Age Adult, Older_Adult
Lymph depletion Yes

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