Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | CD79B | Synonyms | AGM6, B29, IGB, Igbeta | Type of gene | protein-coding |
Chromosome | 17 | Map location | 17q23.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | CD79b molecule |
GTO ID | GTC3578 |
Trial ID | NCT06026319 |
Disease | Non-Hodgkin's Lymphoma | Follicular Lymphoma | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma | Mantle Cell Lymphoma |
Altered gene | CD79B|CD19 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD79b-19 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I Study of Bivalent CD79b and CD19 Directed CAR T Cells in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma |
Year | 2023 |
Country | United States |
Company sponsor | Marcela V. Maus, M.D.,Ph.D. |
Other ID(s) | 23-474 |
Cohort 1 | |||||||||
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