Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD79B Synonyms AGM6, B29, IGB, Igbeta Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD79b molecule

GTO ID GTC3578
Trial ID NCT06026319
Disease Non-Hodgkin's Lymphoma | Follicular Lymphoma | Marginal Zone Lymphoma | Diffuse Large B Cell Lymphoma | Primary Mediastinal Large B-Cell Lymphoma | Mantle Cell Lymphoma
Altered gene CD79B|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD79b-19 CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleA Phase I Study of Bivalent CD79b and CD19 Directed CAR T Cells in Patients With Relapsed/Refractory Non-Hodgkin Lymphoma
Year2023
CountryUnited States
Company sponsorMarcela V. Maus, M.D.,Ph.D.
Other ID(s)23-474

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 24
Age Adult, Older_Adult
Lymph depletion Yes

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