Gene symbol | CLEC12A | Synonyms | CD371, CLL-1, CLL1, DCAL-2, MICL | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.31-p13.2 | dbXrefs | |
Description | C-type lectin domain family 12 member A |
GTO ID | GTC3574 |
Trial ID | NCT06017258 |
Disease | Acute Myeloid Leukemia |
Altered gene | CD371 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CD371-YSNVZ-IL18 CAR-T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase I Trial of CLEc12a (CD371) Targeted ArmoRed Immune Effector Cells in Patients With Relapsed/Refractory Acute Myeloid Leukemia (CLEAR-AML) |
Year | 2023 |
Country | United States |
Company sponsor | Memorial Sloan Kettering Cancer Center |
Other ID(s) | 23-016 |
Cohort 1 | |||||||
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