Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3573
Trial ID NCT06014762
Disease Diffuse Large B Cell Lymphoma | Follicular Lymphoma | Mantle Cell Lymphoma | Marginal Zone Lymphoma | Primary Mediastinal Large B-Cell Lymphoma | Chronic Lymphocytic Leukemia
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment P-CD19CD20-ALLO1
PhasePhase1
Recruitment statusRecruiting
TitleOpen-Label, Multicenter, Phase 1 Study to Assess the Safety of P-CD19CD20-ALLO1 in Subjects With Selected Relapsed/Refractory B Cell Malignancies
Year2024
CountryUnited States
Company sponsorPoseida Therapeutics, Inc.
Other ID(s)P-CD19CD20-ALLO1-001

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 100
Age Adult, Older_Adult
Lymph depletion Yes

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