Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3572
Trial ID NCT06014073
Disease Non-Hodgkin's Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment ATHENA CAR-T cells
Generation2nd
Recruitment statusRecruiting
TitleTRAC and Power3 Genes Knock-out Allogeneic CD19-targeting CAR-T Cell Therapy in r/r B-NHL
Year2023
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-082

Clinical Result

Cohort1: Phase 1
Administration route None
Dosage 1E6 cells/kg, 3E6 cells/kg, 1E7 cells/kg
Donor type Allogeneic
Pts 6~18
Age Adult, Older_Adult
Lymph depletion No
Cohort2: Phase 2
Administration route None
Dosage RP2D
Donor type Allogeneic
Pts 10~12
Age Adult, Older_Adult

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