Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3567
Trial ID NCT06009107
Disease B-Cell Acute Lymphoblastic Leukemia
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HY004
Generation2nd
Recruitment statusNot Recruiting
TitleA Study of HY004 Treatment in Adult Relapsed/Refractory B-precursor Acute Lymphoblastic Leukemia (r/r B-ALL)
Year2024
CountryChina
Company sponsorJuventas Cell Therapy Ltd.
Other ID(s)HY004101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 50
Age Adult, Older_Adult
Lymph depletion Yes

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