Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC3564
Trial ID NCT06006403
Disease Blastic Plasmacytoid Dendritic Cell Neoplasm | Acute Myeloid Leukemia
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD123 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleSafety and Efficacy of CD123-targeted CAR-NK for Relapsed/Refractory Acute Myeloid Leukemia or Blastic Plasmacytoid Dendritic Cell Neoplasm
Year2023
CountryChina
Company sponsorChongqing Precision Biotech Co., Ltd
Other ID(s)PBC050

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1~10E6 cells/kg
Pts 36
Age Adult, Older_Adult
Lymph depletion Yes

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