Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3562
Trial ID NCT06005649
Disease Non-Hodgkin's Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment HY004
Generation2th
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleA Multi-center, Open Label, Single-arm, Phase I/II Clinical Trial of HY004 Cell Injection in the Treatment of Relapsed or Refractory B-Cell Non-Hodgkin's Lymphoma
Year2024
CountryChina
Company sponsorJuventas Cell Therapy Ltd.
Other ID(s)HY004102

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2.0E6 cells/kg
Pts 80
Age Adult, Older_Adult
Lymph depletion Yes

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