Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol GPRC5D Synonyms None Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description G protein-coupled receptor class C group 5 member D

GTO ID GTC3559
Trial ID NCT05998928
Disease Multiple Myeloma
Altered gene BCMA|GPRC5D
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA-GPRC5D CAR-T cells
PhasePhase2
Recruitment statusRecruiting
TitleA Clinical Study to Evaluate the Safety and Efficacy of BCMA-GPRC5D CAR-T in Patients With R/R MM Who Received Three or More Lines of Therapy
Year2023
CountryChina
Company sponsorWuhan Union Hospital, China
Other ID(s)BCMA-GPRC5D CAR-T-cells

Clinical Result

Cohort 1
Administration route infusion
Dosage 4.0E6 ± 50% cells/kg
Pts 10
Age Adult, Older_Adult
Lymph depletion Yes

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