Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

Gene symbol CD33 Synonyms CD33rSiglec, SIGLEC-3, SIGLEC3, p67 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description CD33 molecule

Gene symbol CD38 Synonyms ADPRC 1, ADPRC1, cADPR1 Type of gene protein-coding
Gene perturbation-related omics dataset PertOrg
Description CD38 molecule

Gene symbol COLEC10 Synonyms 3MC3, CL-10, CL-34, CLL1 Type of gene protein-coding
Description collectin subfamily member 10

GTO ID GTC3557
Trial ID NCT05995041
Disease Acute Myeloid Leukemia
Altered gene CLL1|CD33|CD38|CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CAR-T cells
PhasePhase1
Recruitment statusRecruiting
TitleUniversal CAR T Cells for the Treatment of Acute Myeloid Leukemia
Year2023
CountryChina
Company sponsorShenzhen Geno-Immune Medical Institute
Other ID(s)GIMI-IRB-23004

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 30
Age Child, Adult, Older_Adult

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