Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | MS4A1 | Synonyms | B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q12.2 | dbXrefs | |
Description | membrane spanning 4-domains A1 |
GTO ID | GTC3549 |
Trial ID | NCT05990465 |
Disease | Non-Hodgkin's Lymphoma | Diffuse Large B Cell Lymphoma | Follicular Lymphoma | Marginal Zone Lymphoma | Mantle Cell Lymphoma | Burkitt Lymphoma |
Altered gene | CD19|CD20 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | LV20.19 CAR T cells |
Co-treatment | Pirtobrutinib |
Phase | Phase1 |
Recruitment status | Not Recruiting |
Title | Phase I Study of LV20.19 CAR T-cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies |
Year | 2024 |
Country | United States |
Company sponsor | Medical College of Wisconsin |
Other ID(s) | PRO00050826 |
Cohort 1 | |||||||||||
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