Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3549
Trial ID NCT05990465
Disease Non-Hodgkin's Lymphoma | Diffuse Large B Cell Lymphoma | Follicular Lymphoma | Marginal Zone Lymphoma | Mantle Cell Lymphoma | Burkitt Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment LV20.19 CAR T cells
Co-treatment Pirtobrutinib
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase I Study of LV20.19 CAR T-cells in Combination With Pirtobrutinib for Relapsed, Refractory B-cell Malignancies
Year2024
CountryUnited States
Company sponsorMedical College of Wisconsin
Other ID(s)PRO00050826

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2.5E6 cells/kg
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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