Basic Information

Gene symbol CTAG1B Synonyms CTAG, ESO1, CT6.1, CTAG1, LAGE-2, LAGE2B, NY-ESO-1 Type of gene protein-coding
Description cancer/testis antigen 1B

GTO ID GTC3548
Trial ID NCT05989828
Disease Triple-Receptor Negative Breast Cancer
Altered gene NY-ESO-1
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment NY-ESO-1 TCR-T cells
Co-treatment Biopsy
HLAHLA-A2
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase Ib Clinical Trial of Autologous Anti-NY-ESO-1 TCR-Engineered T Cells in Patients With Relapsed/Refractory Locally Advanced or Metastatic NY-ESO-1-Expressing Triple Negative Breast Cancer
Year2023
CountryUnited States
Company sponsorUniversity of Southern California
Other ID(s)1B-23-1|NCI-2023-04697|1B-23-1|P30CA014089|2018-002987-14

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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