Gene symbol | CD19 | Synonyms | B4, CVID3 | Type of gene | protein-coding |
Chromosome | 16 | Map location | 16p11.2 | dbXrefs | |
Description | CD19 molecule |
Gene symbol | IL18 | Synonyms | IGIF, IL-18, IL-1g, IL1F4 | Type of gene | protein-coding |
Chromosome | 11 | Map location | 11q23.1 | dbXrefs | |
Gene perturbation-related omics dataset | PertOrg | ||||
Description | interleukin 18 |
GTO ID | GTC3547 |
Trial ID | NCT05989204 |
Disease | Non-Hodgkin's Lymphoma |
Altered gene | CD19|IL-18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | TmCD19-IL18 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | Phase I Trial of TmCD19-IL18 CAR T Cells in Patients With Relapsed or Refractory CD19+ Cancers |
Year | 2023 |
Country | United States |
Company sponsor | University of Pennsylvania |
Other ID(s) | UPCC 12423 |
Cohort 1 | |||||||||||
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