Gene symbol | CD22 | Synonyms | SIGLEC-2, SIGLEC2 | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.12 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | CD22 molecule |
GTO ID | GTC3528 |
Trial ID | NCT05972720 |
Disease | Large B-Cell Lymphoma |
Altered gene | CD22 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | firi-cel|Firicabtagene autoleucel |
Phase | Phase2 |
Recruitment status | Recruiting |
Title | An Open-label, Multicenter Phase 2 Study Evaluating the Efficacy and Safety of Firi-cel, a CD22-directed Autologous Chimeric Antigen Receptor (CAR) T-cell Therapy in Patients With Relapsed/Refractory Large B-Cell Lymphoma After CD19-directed CAR T-cell Therapy |
Year | 2023 |
Country | United States |
Company sponsor | CARGO Therapeutics |
Other ID(s) | CRG-022-101 |
Cohort 1 | |||||||||||
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