Basic Information

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3528
Trial ID NCT05972720
Disease Large B-Cell Lymphoma
Altered gene CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment firi-cel|Firicabtagene autoleucel
PhasePhase2
Recruitment statusRecruiting
TitleAn Open-label, Multicenter Phase 2 Study Evaluating the Efficacy and Safety of Firi-cel, a CD22-directed Autologous Chimeric Antigen Receptor (CAR) T-cell Therapy in Patients With Relapsed/Refractory Large B-Cell Lymphoma After CD19-directed CAR T-cell Therapy
Year2023
CountryUnited States
Company sponsorCARGO Therapeutics
Other ID(s)CRG-022-101

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 123
Age Adult, Older_Adult
Lymph depletion Yes

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