Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3523
Trial ID NCT05963217
Disease B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Small Lymphocytic Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TBI-2001
PhasePhase1
Recruitment statusRecruiting
TitlePhase I/Ib Study of TBI-2001 for Patients With Relapsed or Refractory CD19+ B-cell Lymphoma, Chronic Lymphocytic Leukemia (CLL), Small Lymphocytic Lymphoma (SLL)
Year2023
CountryCanada
Company sponsorUniversity Health Network, Toronto
Other ID(s)TBI-200101

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 3E5 cells/kg, 1E6 cells/kg, 3Ecells/kg
Donor type autologous
Pts 19
Age Adult, Older_Adult
Lymph depletion Yes

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