Basic Information

Gene symbol MSLN Synonyms MPF, SMRP Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mesothelin

GTO ID GTC3522
Trial ID NCT05963100
Disease Ovarian Cancer
Altered gene MSLN
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment TCR-like CAR-T
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleClinical Study of TCR-like CAR-T Cell Targeted MSLN in the Treatment of Ovarian Cancer
Year2023
CountryChina
Company sponsorZhongda Hospital
Other ID(s)2023010142

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg, 1E7 cells/kg, 3E6 cells/kg, 2E7 cells/kg
Pts 10
Age Adult, Older_Adult

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