Basic Information

Gene symbol CD86 Synonyms B7-2, B7.2, B70, CD28LG2, LAB72 Type of gene protein-coding
Description CD86 molecule

Gene symbol PDCD1 Synonyms CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description programmed cell death 1

GTO ID GTC3520
Trial ID NCT05961111
Disease Sarcoma | Carcinoma | Digestive Cancer | Breast Cancer | Lung Cancer | Brain Cancer | Melanoma | Gynecologic Cancer | Head and Neck Cancer | Kidney Cancer
Altered gene CD86|PDCD1
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment R130
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleAn Open, Single-armed, Clinical Safety and Efficacy Study on Oncolytic Virus Injection (R130 OV) for the Treatment of Advanced Solid Tumors
Year2023
CountryChina
Company sponsorShanghai Yunying Medical Technology
Other ID(s)LYCH-R130
Vector information
Vectorherpes simplex virus

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 1E8 PFU/mL
Pts 20
Age Adult, Older_Adult

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