Basic Information

Gene symbol CLDN18 Synonyms SFTA5, SFTPJ Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description claudin 18

GTO ID GTC3517
Trial ID NCT05952375
Disease Gastric Cancer
Altered gene CLDN18
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment XKDCT086
PhaseNot Applicable
Recruitment statusRecruiting
TitleExploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial
Year2023
CountryChina
Company sponsorThe Affiliated Hospital of Qingdao University
Other ID(s)XKDCT086

Clinical Result

Cohort 1
Administration route None
Pts 9
Age Adult, Older_Adult
Lymph depletion Yes

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