Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
GTO ID | GTC3517 |
Trial ID | NCT05952375 |
Disease | Gastric Cancer |
Altered gene | CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | XKDCT086 |
Phase | Not Applicable |
Recruitment status | Recruiting |
Title | Exploratory Clinical Trial on the Safety, Efficacy, and Pharmacokinetics of XKDCT086 (iPD-1-Claudin18.2-CAR-T) in Claudin 18.2 Positive Advanced Solid Malignant Tumors: a Single Center, Single Arm, Dose-increasing Trial |
Year | 2023 |
Country | China |
Company sponsor | The Affiliated Hospital of Qingdao University |
Other ID(s) | XKDCT086 |
Cohort 1 | |||||||||
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