Basic Information

Gene symbol IL3RA Synonyms CD123, IL-3R-alpha, IL3R, IL3RAY, IL3RX, IL3RY, hIL-3Ra Type of gene protein-coding
Description interleukin 3 receptor subunit alpha

GTO ID GTC3514
Trial ID NCT05949125
Disease Acute Myeloid Leukemia
Altered gene CD123
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Allo-RevCAR01-T
PhasePhase1
Recruitment statusRecruiting
TitleMulticenter, Open-label, Phase 1 Study of Allo-RevCAR01-T-CD123 Consisting of Genetically Modified T Cells Carrying Reverse Chimeric Antigen Receptors (Allo RevCAR01 T) in Combination With CD123 Target Module (R-TM123) for the Treatment of Patients With Selected Hematologic Malignancies Positive for CD123
Year2024
CountryGermany
Company sponsorAvenCell Europe GmbH
Other ID(s)AVC-201-01|2022-501797-19-00

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 37
Age Adult, Older_Adult
Lymph depletion Yes

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