Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3512
Trial ID NCT05947487
Disease Solid Tumor
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD70 CAR-T cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitlePhase I/II Study of CD70 Targeted CAR-T Cell Treatment in CD70 Positive Advanced/Metastatic Solid Tumors
Year2023
CountryChina
Company sponsorChinese PLA General Hospital
Other ID(s)CHN-PLAGH-BT-080

Clinical Result

Cohort 1
Administration route infusion
Dosage 1E6 cells/kg, 3E6 cells/kg, 1E7cells/kg
Donor type autologous
Pts 30
Age Adult, Older_Adult
Lymph depletion Yes

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