Gene symbol | CLDN18 | Synonyms | SFTA5, SFTPJ | Type of gene | protein-coding |
Chromosome | 3 | Map location | 3q22.3 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | PertOrg | ||||
Description | claudin 18 |
GTO ID | GTC3511 |
Trial ID | NCT05946226 |
Disease | Digestive System Tumor |
Altered gene | CLDN18 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | IMC002 |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I, Open-label, Multi-center, Dose-escalation Study to Evaluate the Safety, Feasibility, and Preliminary Efficacy of IMC002 in Patients With Claudin18.2-positive Advanced Digestive System Tumors |
Year | 2023 |
Country | China |
Company sponsor | Suzhou Immunofoco Biotechnology Co., Ltd |
Other ID(s) | IMC002-RT01 |
Cohort 1 | |||||||||||||
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