| Gene symbol | CD33 | Synonyms | CD33rSiglec, SIGLEC-3, SIGLEC3, p67 | Type of gene | protein-coding |
| Chromosome | 19 | Map location | 19q13.41 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | CD33 molecule | ||||
| GTO ID | GTC3510 |
| Trial ID | NCT05945849 |
| Disease | Acute Myeloid Leukemia |
| Altered gene | CD33 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | CART33 |
| Co-treatment | CD33KO-HSPC |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | Phase 1 Study of Lentivirally Transduced T Cells Engineered to Contain Anti-CD33 Linked to TCRζ And 4-1BB Signaling Domains In Combination With CD33KO-HSPC In Subjects With Refractory Or Relapsed Acute Myeloid Leukemia |
| Year | 2024 |
| Country | United States |
| Company sponsor | University of Pennsylvania |
| Other ID(s) | CART33 |
| Cohort 1 | |||||||
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