Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3505
Trial ID NCT05938725
Disease Lupus Nephritis
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment KYV-101
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleKYSA-1: A Phase 1/2, Open-Label, Multicenter Study of KYV-101, an Autologous Fully-Human Anti-CD19 Chimeric Antigen Receptor T-Cell (CD19 CAR T) Therapy, in Subjects With Refractory Lupus Nephritis
Year2023
CountryUnited States
Company sponsorKyverna Therapeutics
Other ID(s)KYSA-1|KYV101-001

Clinical Result

Cohort 1
Administration route infusion
Donor type autologous
Pts 32
Age Adult, Older_Adult
Lymph depletion Yes

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