Basic Information

Gene symbol KRAS Synonyms C-K-RAS, C-K-RAS, CFC2, K-RAS2A, K-RAS2B, K-RAS4A, K-RAS4B, K-Ras, K-Ras 2, KI-RAS, KRAS1, KRAS2, NS, NS3, OES, RALD, RASK2, c-Ki-ras, c-Ki-ras2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description KRAS proto-oncogene, GTPase

GTO ID GTC3501
Trial ID NCT05933668
Disease Advanced Solid Tumor
Altered gene KRAS
Therapeutic/Target gene Target gene
TherapyTCR-T cell
Treatment YK0901
HLAHLA-A*11:01
PhasePhase1
Recruitment statusNot Recruiting
TitlePhase I Clinical Study of YK0901 Injection for the Treatment of Advanced Solid Tumors With HLA-A * 11:01 Positive and KRAS G12V Mutation
Year2023
CountryChina
Company sponsorPeking University
Other ID(s)YK0901

Clinical Result

Cohort 1
Administration route infusion
Dosage 0.1~50E9 cells
Donor type autologous
Age Adult, Older_Adult
Lymph depletion Yes

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