Basic Information

Gene symbol TACSTD2 Synonyms EGP-1, EGP1, GA733-1, GA7331, GP50, M1S1, TROP2 Type of gene protein-coding
Description tumor associated calcium signal transducer 2

GTO ID GTC3490
Trial ID NCT05922930
Disease Pancreatic Cancer | Ovarian Cancer | Adenocarcinoma
Altered gene TROP2
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment TROP2 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy of TROP2 CAR Engineered IL15-transduced Cord Blood-derived NK Cells Delivered Intraperitoneally for the Management of Platinum Resistant Ovarian Cancer, Mesonephric-like Adenocarcinoma, and Pancreatic Cancer
Year2023
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2022-0687|NCI-2023-05027

Clinical Result

Cohort 1
Administration route intraperitoneal infusion
Pts 51
Age Adult, Older_Adult
Lymph depletion Yes

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