Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3468
Trial ID NCT05888493
Disease Follicular Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment Kymriah|Tisagenlecleucel
Generation2nd
PhasePhase3
Recruitment statusNot Recruiting
TitleA Phase III Trial Comparing Tisagenlecleucel to Standard of Care (SoC) in Adult Participants With r/r Follicular Lymphoma
Year2023
CountrySwitzerland
Company sponsorNovartis Pharmaceuticals
Other ID(s)CCTL019E2301|2023-503452-27-00
Vector information
Vectorlentivirus
ConstructscFv-4-1BB-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.6~6E8 cells
Donor type Autologous
Pts 108
Age Adult, Older_Adult
Lymph depletion Yes

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