Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

GTO ID GTC3451
Trial ID NCT05870917
Disease Plasma Cell Leukemia
Altered gene BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment BCMA CAR-T cells
Co-treatment Bortezomib, Lenalidomide and Dexamethasone
PhasePhase2
Recruitment statusRecruiting
TitleA Study of Ve-VRD or S-VRD Combined With CART-ASCT-CART2 Treatment in Patients With Primary Plasma Cell Leukemia
Year2023
CountryChina
Company sponsorInstitute of Hematology & Blood Diseases Hospital
Other ID(s)CAC-PPCL-001

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 2~4E6 (±20%) cells/kg, double infusion
Donor type Autologous
Pts 20
Age Adult, Older_Adult

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