Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3439
Trial ID NCT05858684
Disease Systemic Lupus Erythematosus
Altered gene CD19|BCMA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GC012F
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleDual Target CAR-T Cell Treatment for Refractory Systemic Lupus Erythematosus (SLE) Patients
Year2023
CountryChina
Company sponsorRenJi Hospital
Other ID(s)GC012F-615

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.5E5 cells/kg (±20%), 1E5 cells/kg (±20%), 2E5 cells/kg (±20%), 3E5 cells/kg (±20%)
Pts 18
Age Adult, Older_Adult

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