Basic Information

Gene symbol CD86 Synonyms B7-2, B7.2, B70, CD28LG2, LAB72 Type of gene protein-coding
Description CD86 molecule

Gene symbol PDCD1 Synonyms CD279, PD-1, PD1, SLEB2, hPD-1, hPD-l, hSLE1 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description programmed cell death 1

GTO ID GTC3437
Trial ID NCT05851456
Disease Osteosarcoma | Soft Tissue Sarcoma | Bone Tumor
Altered gene CD86|PDCD1
Therapeutic/Target gene Therapeutic gene
TherapyGene transfer
Treatment R130
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleA Clinical Safety and Efficacy Study on Oncolytic Virus Injection (R130) for the Treatment of Relapsed/Refractory Bone and Soft Tissue Tumors
Year2023
CountryChina
Company sponsorShanghai Yunying Medical Technology
Other ID(s)XAHH-R130-BSTT
Vector information
Vectorherpes simplex virus

Clinical Result

Cohort 1
Administration route intratumoral injection
Dosage 1E8 PFU/mL
Pts 20
Age Child, Adult, Older_Adult

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