Basic Information

Gene symbol TNFRSF17 Synonyms BCM, BCMA, CD269, TNFRSF13A Type of gene protein-coding
Description TNF receptor superfamily member 17

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3428
Trial ID NCT05840107
Disease Multiple Myeloma
Altered gene BCMA|CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment GC012F
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleStudy of FasT CAR-T GC012F Injection NDMM Patients
Year2023
CountryChina
Company sponsorShanghai Changzheng Hospital
Other ID(s)GC012F-322

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 0.6E5 cells/kg, 1.5E5 cells/kg, 3E5 cells/kg
Donor type Autologous
Pts 18
Age Adult, Older_Adult
Lymph depletion Yes

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