| Gene symbol | IL1RN | Synonyms | CRMO2, DIRA, ICIL-1RA, IL-1RN, IL-1ra, IL-1ra3, IL1F3, IL1RA, IRAP, MVCD4 | Type of gene | protein-coding |
| Chromosome | 2 | Map location | 2q14.1 | dbXrefs | |
| Gene perturbation-related omics dataset | PerturbAtlas | ||||
| Description | interleukin 1 receptor antagonist | ||||
| GTO ID | GTC3423 |
| Trial ID | NCT05835895 |
| Disease | Knee Osteoarthritis |
| Altered gene | IL1RN |
| Therapeutic/Target gene | Therapeutic gene |
| Therapy | Gene transfer |
| Treatment | GNSC-001|sc-rAAV2.5IL-1Ra |
| Phase | Phase1 |
| Recruitment status | Active, Not Recruiting |
| Title | A Phase 1b, Randomized, Double-Blinded, Placebo-Controlled Dose Ranging Study to Evaluate Safety, Tolerability and Pharmacodynamics of a Single Intra-articular Injection of GNSC-001 Gene Therapy in Subjects With Osteoarthritis of the Knee |
| Year | 2023 |
| Country | United States |
| Company sponsor | Genascence Corporation |
| Other ID(s) | CPRO-22-001|CLIN2-14265 |
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| Cohort 1 | |||||||||
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