| Gene symbol | CD276 | Synonyms | 4Ig-B7-H3, B7-H3, B7H3, B7RP-2 | Type of gene | protein-coding |
| Chromosome | 15 | Map location | 15q24.1 | dbXrefs | |
| Description | CD276 molecule | ||||
| GTO ID | GTC3422 |
| Trial ID | NCT05835687 |
| Disease | Diffuse Midline Glioma | Atypical Teratoid Rhabdoid Tumor | Glioblastoma | Central Nervous System Neoplasm | Brain Ependymoma | Medulloblastoma | High Grade Glioma |
| Altered gene | CD276 |
| Therapeutic/Target gene | Target gene |
| Therapy | CAR-T cell |
| Treatment | B7-H3 CAR-T cells |
| Generation | 3rd |
| Phase | Phase1 |
| Recruitment status | Recruiting |
| Title | Loc3CAR: Locoregional Delivery of B7-H3-CAR T Cells for Pediatric Patients With Primary CNS Tumors |
| Year | 2023 |
| Country | United States |
| Company sponsor | St. Jude Children's Research Hospital |
| Other ID(s) | Loc3CAR|NCI-2023-02484 |
| Vector information | |||||
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| Cohort 1 | |||||||||
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