Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3413
Trial ID NCT05826535
Disease Non-Hodgkin's Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment IMPT-314
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy of IMPT-314 in R/R Aggressive B-cell
Year2023
CountryUnited States
Company sponsorImmPACT Bio
Other ID(s)MPCT-012L

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E8 cells (±20%), 3E8 cells (±20%), single infusion
Donor type Autologous
Pts 50
Age Adult, Older_Adult
Lymph depletion Yes

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