Basic Information

Gene symbol MUC1 Synonyms ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas
Description mucin 1, cell surface associated

GTO ID GTC3402
Trial ID NCT05812326
Disease Breast Cancer | Female Breast Cancer
Altered gene MUC1
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment AJMUC1
Generation2nd
PhasePhase1|Phase2
Recruitment statusCompleted
TitlePD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer
Year2023
CountryChina
Company sponsorSun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Other ID(s)2019-KY-001-003

Clinical Result

Cohort 1
Administration route None
Dosage 3E5 cells/kg, 1E6 cells/kg, 3E6 cells/kg
Donor type Autologous
Pts 15
Age Adult, Older_Adult

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