Gene symbol | MUC1 | Synonyms | ADMCKD, ADMCKD1, ADTKD2, CA 15-3, CD227, Ca15-3, EMA, H23AG, KL-6, MAM6, MCD, MCKD, MCKD1, MUC-1, MUC-1/SEC, MUC-1/X, MUC1/ZD, PEM, PEMT, PUM | Type of gene | protein-coding |
Chromosome | 1 | Map location | 1q22 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | mucin 1, cell surface associated |
GTO ID | GTC3402 |
Trial ID | NCT05812326 |
Disease | Breast Cancer | Female Breast Cancer |
Altered gene | MUC1 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | AJMUC1 |
Generation | 2nd |
Phase | Phase1|Phase2 |
Recruitment status | Completed |
Title | PD-1 Knockout Anti-MUC1 CAR-T Cells in the Treatment of Advanced Breast Cancer |
Year | 2023 |
Country | China |
Company sponsor | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University |
Other ID(s) | 2019-KY-001-003 |
Cohort 1 | |||||||||||
|