Basic Information

Gene symbol PSCA Synonyms PRO232, lncPSCA Type of gene protein-coding
Description prostate stem cell antigen

GTO ID GTC3399
Trial ID NCT05805371
Disease Castration-Resistant Prostate Carcinoma | Prostate Cancer | Prostate Carcinoma
Altered gene PSCA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment PSCA CAR-T cells
Generation2nd
PhasePhase1
Recruitment statusRecruiting
TitlePSCA-Targeting CAR-T Cells Plus or Minus Radiation for the Treatment of Patients With PSCA+ Metastatic Castration-Resistant Prostate Cancer
Year2023
CountryUnited States
Company sponsorCity of Hope Medical Center
Other ID(s)22378|NCI-2023-02186|22378|P30CA033572

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 21
Age Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph