Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol CD22 Synonyms SIGLEC-2, SIGLEC2 Type of gene protein-coding
Gene perturbation-related omics dataset PerturbAtlas | PertOrg
Description CD22 molecule

GTO ID GTC3388
Trial ID NCT05797948
Disease B-Cell Non-Hodgkin's Lymphoma
Altered gene CD19|CD22
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD22 CAR-T cells
Co-treatment Obinutuzumab, Zanubrutinib, Lenalidomide
Recruitment statusRecruiting
TitleGZL Sequential CD19/CD22 CAR-T in Relapsed or Refractory B-cell Non-Hodgkin Lymphoma
Year2023
CountryChina
Company sponsorThe First Affiliated Hospital of Soochow University
Other ID(s)GZL

Clinical Result

Cohort 1
Administration route None
Dosage 1E7 cells/kg
Pts 20
Age Adult, Older_Adult
Lymph depletion Yes

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