Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

Gene symbol MS4A1 Synonyms B1, Bp35, CD20, CVID5, FMC7, LEU-16, S7 Type of gene protein-coding
Description membrane spanning 4-domains A1

GTO ID GTC3387
Trial ID NCT05797233
Disease B-Cell Chronic Lymphocytic Leukemia | B-Cell Lymphoma
Altered gene CD19|CD20
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19/CD20 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleTrial of Anti-CD19 and Anti-CD20 Bicistronic Chimeric Antigen Receptor T Cells for Treating B-Cell Malignancies
Year2023
CountryUnited States
Company sponsorNational Cancer Institute (NCI)
Other ID(s)10001524|001524-C

Clinical Result

Cohort 1
Administration route None
Dosage 0.66~10E6 cells/kg
Pts 58
Age Adult, Older_Adult
Lymph depletion Yes

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