Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3386
Trial ID NCT05795595
Disease Malignant Pleural Mesothelioma | Pancreatic Adenocarcinoma | Exocervical Carcinoma | Clear Cell Renal Cell Carcinoma | Esophageal Carcinoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CTX131
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Safety and Efficacy Study Evaluating CTX131 in Adult Subjects With Relapsed or Refractory Solid Tumors
Year2023
CountryUnited States
Company sponsorCRISPR Therapeutics AG
Other ID(s)CRSP-ONC-005

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Allogeneic
Pts 250
Age Adult, Older_Adult

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