Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3376
Trial ID NCT05779930
Disease B-Cell Leukemia | B-Cell Lymphoma | Non-Hodgkin's Lymphoma | Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhaseEarly_Phase1
Recruitment statusNot Recruiting
TitleSafety and Feasibility of CD19 CAR T Cells Using CliniMACS Prodigy for Relapsed/Refractory CD19 Positive ALL and NHL
Year2023
CountryUnited States
Company sponsorNationwide Children's Hospital
Other ID(s)AutoCAR19

Clinical Result

Cohort 1
Administration route None
Dosage <50 kg: 0.3~1E6 cells/kg; ≥50 kg: 0.3~1E8 cells
Donor type Autologous
Pts 12
Age Child, Adult
Lymph depletion Yes

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