Gene symbol | LGR5 | Synonyms | FEX, GPR49, GPR67, GRP49, HG38 | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12q21.1 | dbXrefs | |
Gene perturbation-related omics dataset | PerturbAtlas | ||||
Description | leucine rich repeat containing G protein-coupled receptor 5 |
GTO ID | GTC3361 |
Trial ID | NCT05759728 |
Disease | Colorectal Cancer |
Altered gene | LGR5 |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | CNA3103 |
Phase | Phase1|Phase2 |
Recruitment status | Not Recruiting |
Title | A Study of CNA3103 (LGR5-targeted, Autologous CAR-T Cells) Administered to Subjects With Metastatic Colorectal Cancer |
Year | 2023 |
Country | Australia |
Company sponsor | Carina Biotech Pty Ltd |
Other ID(s) | CNA3103-001 |
Cohort 1 | |||||||||||||
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