Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3358
Trial ID NCT05757219
Disease Diffuse Large B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment YesCAR-Ta|Axicabtagene Ciloleucel|axi-cel
Generation2nd
PhasePhase2
Recruitment statusRecruiting
TitleItacitinib Pre-modulation in DLBCL Receiving CAR T Cell Therapy
Year2023
CountryUnited States
Company sponsorH. Lee Moffitt Cancer Center and Research Institute
Other ID(s)MCC-21892
Vector information
Vectorlentivirus
ConstructscFv-CD28-CD3ζ

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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