Gene symbol | ADGRE2 | Synonyms | CD312, CD97, EMR2, VBU | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19p13.12 | dbXrefs | |
Description | adhesion G protein-coupled receptor E2 |
Gene symbol | CLEC12A | Synonyms | CD371, CLL-1, CLL1, DCAL-2, MICL | Type of gene | protein-coding |
Chromosome | 12 | Map location | 12p13.31-p13.2 | dbXrefs | |
Description | C-type lectin domain family 12 member A |
GTO ID | GTC3353 |
Trial ID | NCT05748197 |
Disease | Acute Myeloid Leukemia |
Altered gene | ADGRE2|CLEC12A |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | ADCLEC.syn1 CAR T cells |
Phase | Phase1 |
Recruitment status | Recruiting |
Title | A Phase I Study of ADCLEC.syn1 CAR T Cells in Adult Patients With Relapsed or Refractory Acute Myeloid Leukemia |
Year | 2024 |
Country | United States |
Company sponsor | Memorial Sloan Kettering Cancer Center |
Other ID(s) | 23-002 |
Cohort 1 | |||||||||||
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