Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3341
Trial ID NCT05739227
Disease B-Cell Lymphoma | Chronic Lymphocytic Leukemia | Acute Lymphoblastic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD19 CAR-NK cells
PhaseEarly_Phase1
Recruitment statusRecruiting
TitleSafety and Efficacy of Allogenic CD19-CAR-NK Cells in Treatmenting r/r B-cell Hematologic Malignancies
Year2023
CountryChina
Company sponsorXuzhou Medical University
Other ID(s)XYFY2022-KL252-01

Clinical Result

Cohort 1
Administration route None
Dosage 1E6 cells/kg, 5E6 cells/kg, 2E7 cells/kg
Donor type Allogeneic
Pts 12
Age Adult, Older_Adult
Lymph depletion Yes

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