Gene symbol | CEACAM5 | Synonyms | CD66e, CEA | Type of gene | protein-coding |
Chromosome | 19 | Map location | 19q13.2 | dbXrefs | |
Description | CEA cell adhesion molecule 5 |
GTO ID | GTC3338 |
Trial ID | NCT05736731 |
Disease | Pancreatic Cancer | Lung Non-Squamous Non-Small Cell Carcinoma | Lung Non-Small Cell Carcinoma | Colorectal Cancer | Colorectal Adenocarcinoma |
Altered gene | CEA |
Therapeutic/Target gene | Target gene |
Therapy | CAR-T cell |
Treatment | A2B530 |
Phase | Phase1|Phase2 |
Recruitment status | Recruiting |
Title | A Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression |
Year | 2023 |
Country | United States |
Company sponsor | A2 Biotherapeutics Inc. |
Other ID(s) | A2B530-101 |
Cohort 1 | |||||||||||
|