Basic Information

Gene symbol CEACAM5 Synonyms CD66e, CEA Type of gene protein-coding
Description CEA cell adhesion molecule 5

GTO ID GTC3338
Trial ID NCT05736731
Disease Pancreatic Cancer | Lung Non-Squamous Non-Small Cell Carcinoma | Lung Non-Small Cell Carcinoma | Colorectal Cancer | Colorectal Adenocarcinoma
Altered gene CEA
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment A2B530
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleA Study to Evaluate the Safety and Efficacy of A2B530, a Logic-gated CAR T, in Subjects With Solid Tumors That Express CEA and Have Lost HLA-A*02 Expression
Year2023
CountryUnited States
Company sponsorA2 Biotherapeutics Inc.
Other ID(s)A2B530-101

Clinical Result

Cohort 1
Administration route intravenous infusion
Donor type Autologous
Pts 160
Age Adult, Older_Adult
Lymph depletion Yes

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