Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3323
Trial ID NCT05705570
Disease Acute Lymphoblastic Leukemia | Chronic Lymphocytic Leukemia | B-Cell Lymphoma
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhasePhase1
Recruitment statusNot Recruiting
TitleA Phase I Clinical Trial Using Genetically Engineered Autologous T Cells to Express Chimeric Antigen Receptor (CAR) for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies
Year2023
CountryBrazil
Company sponsorHospital Israelita Albert Einstein
Other ID(s)30173220.5.0000.0071

Clinical Result

Cohort 1
Administration route None
Dosage 1E5 cells/kg, 1E6 cells/kg, 2E6 cells/kg
Donor type Autologous
Pts 30
Age Child, Adult, Older_Adult
Lymph depletion Yes

Relationship Graph

Overview of Knowledge Graph