Basic Information

Gene symbol CD70 Synonyms CD27-L, CD27L, CD27LG, LPFS3, TNFSF7, TNLG8A Type of gene protein-coding
Description CD70 molecule

GTO ID GTC3322
Trial ID NCT05703854
Disease Osteosarcoma | Mesothelioma | Renal Cell Carcinoma
Altered gene CD70
Therapeutic/Target gene Target gene
TherapyCAR-NK cell
Treatment CD70 CAR-NK cells
PhasePhase1|Phase2
Recruitment statusRecruiting
TitleStudy of CAR.70-engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Advanced Renal Cell Carcinoma, Mesothelioma and Osteosarcoma
Year2023
CountryUnited States
Company sponsorM.D. Anderson Cancer Center
Other ID(s)2021-0443|NCI-2023-00469

Clinical Result

Cohort 1
Administration route intravenous infusion
Pts 50
Age Adult, Older_Adult
Lymph depletion Yes

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