Basic Information

Gene symbol CD19 Synonyms B4, CVID3 Type of gene protein-coding
Description CD19 molecule

GTO ID GTC3321
Trial ID NCT05702853
Disease B-Cell Non-Hodgkin's Lymphoma | Chronic Lymphocytic Leukemia
Altered gene CD19
Therapeutic/Target gene Target gene
TherapyCAR-T cell
Treatment CD19 CAR-T cells
PhasePhase1|Phase2
Recruitment statusNot Recruiting
TitleMetabolically Fit CD19 CAR T-cell Therapy With CD34 Selection in Patients With CD19+ Relapsed/Refractory NHL, CLL/SLL
Year2023
CountryUnited States
Company sponsorMedical University of South Carolina
Other ID(s)103351

Clinical Result

Cohort 1
Administration route intravenous infusion
Dosage 1E6 cells/kg (±20%), 1.5E6 cells/kg (±20%), 2E6 cells/kg (±20%)
Pts 27
Age Adult, Older_Adult
Lymph depletion Yes

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